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  Morphogenesis, Signaling, Modeling
  Dynamics and Expression of plant Genomes
  Adaptation of Plants to the Environment
  Reproduction and Seeds
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Teams of the APE department « Adaptation of Plants to the Environment » study the answers to environmental restraints on the physiological, metabolic and developmental point of view using mainly genetic, genomic and molecular approaches. The department is focussed on physical (abiotic) restraints as nitrogen availability limitation and/or water, cold, osmotic stress… Our aim is to understand what is the onset of mechanisms responding to these restraints and what genes are controlling these answers and its natural variability. Integration analysis of these regulations at the whole plant level and the following of parameters which govern plant growth (leaf or root level) and also the onset of productivity or fitness are studied. We are mainly working on the model plant Arabidopsis thaliana and on the agronomical important crop: maize. APE possess competences at different levels and particularly on nitrogen metabolism and its recycling, water use efficiency, quantitative genetics, natural variation analysis and phloem signalisation…

 

Groups

The « Management of nitrogen and crops productivity » team tries to identify the limiting steps of absorption, assimilation and recycling of nitrogen during growth and plant development in general and of cereals more precisely. The general objective is to better understand and improve Nitrogen Use Efficiency (NUE) in maize and wheat.

The « Nitrogen-Pathogen Interactions» (NPI) team studies the mechanisms and the genetic control of the adaptation of Arabidopsis thaliana’s response to the infection by necrotrophic pathogens in conditions of nitrogen limitation

The « Phloem, transport and signalisation» team studies proteins of the phloem playing a role in sieve flux regulation in vascular tissues and on sugar distribution. Proteins role in stress adaptation, in plant development and architecture are equally studied.

The «Nitrogen Use, Transport and signaling» (NUTS) team studies via a molecular physiology approach, growth and plant metabolism, from the root to the seed grown in different conditions of nitrogen nutrition. Efforts are focussed on nitrate and nitrite transport in whole plant and on signalling of nitrogen deficiency. Finally we are exploiting natural Arabidopsis variation to identify and study plant adaptation strategies to limiting nitrogen providing.

The «Senescence, Autophagy, Nutrient recycling and nitrogen use efficiency» team studies mechanisms and genetic controls of recycling of nitrogen nutriments mobilisation during plant development and in response to environmental factors. The team is particularly interested in the role of the enzymes: glutamine synthase and asparagine synthase, in the role of autophagy in organic sources of nitrogen in recycling of protein nitrogen and in nutritional regulation by the TOR (Target Of Rapamycin).kinase signalling pathway.

The «Variation » (VAR) team is using genomics and genetics strategies (including quantitative genetics) and bioinformatics to understand the functioning of the genes and the networks of genes involved in controlling complex traits variation like responses to abiotic stress (drought, cold, ...) and to understand epigenetic regulation. Natural variation segregating among Arabidopsis or tomato populations is particularly exploited to identify new mechanisms and new players in these pathways.

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