IJPB-Méiose et recombinaison

généralités

JP Bourgin

accès

comité de direction

structures cellulaires, signalisation et morphogenèse

dynamique et expression des génomes

adaptation des plantes à leur environnement

reproduction et graines

cytologie et imagerie végétale

biochimie

chimie du végétal

phénotypage arabidopsis

ressources arabidopsis

ressources brachypodium

secrétariat

communication

informatique

installations expérimentales

atelier

laverie

magasin

Recombinaison méiotique chez les polyploïdes

généralités
accès
contact
équipes
publications

Mots-clés :Arabidopsis thaliana - Physcomitrella patens- méiose - recombinaison méiotique - recombinaison mitotique- Reconnaissance des mésappariements - ciblage génique - mutants

Ecole(s) doctorale(s) de rattachement :ED 145 Sciences du végétal

Contacts :

Institut Jean-Pierre Bourgin, UMR1318 INRA-AgroParisTech
Bâtiment 7
INRA Centre de Versailles-Grignon
Route de St-Cyr (RD10)
78026 Versailles Cedex France

tél : +33 (0)1 30 83 30 00 - fax : +33 (0)1 30 83 33 19

	Eric Jenczewski Chargé de recherche
	Laurie Grandont Doctorant
	Camille Genevriez Stage de fin d'étude d'ingénieur VetAgro Sup du 26/03/12 au 26/08/12

	Catherine Marquis Adjoint Technique
	Andrew Lloyd post doc (ANR) du 01/07/2011 au 30/06/2013.
	Anciens membres de l'équipe

Résumé :

It is now clearly established that all flowering plants have experienced at least one and usually several rounds of whole genome duplications (WGD) during the course of their evolution (Soltis et al. 2009; van de Peer et al., 2009). Nearly 30% of existing flowering plants are polyploids (Wood et al. 2009), including most of the world’s important crops, such as wheat, cotton or oilseed rape.

One immediate consequence of polyploidy is an increase in the number of chromosomes that can compete for pairing, synapsis and recombination at meiosis. In newly-formed synthetic or natural polyploids, the presence of more than two partners usually leads to abnormal meiosis with multiple or illegitimate chiasmatic associations that result in chromosome misegregation, aneuploidy and partial fertility (Ramsey and Schemske 2002). By contrast, extant wild and cultivated polyploids display a clear tendency towards a diploid-like meiotic behavior. In allopolyploid species, which arise via hybridization between different species, regular meiosis requires a non-random assortment of chromosomes into pairs with COs being exclusively formed between homologous rather than homeologous chromosomes (i.e. inherited from different progenitors). Such a cytological diploidization is genetically controlled in many polyploid species but the gene(s) responsible for this phenotype are still to be identified in all but one case (Ph1 in wheat). Likewise, we don't know how meiotic recombination genes evolved post-WGD, if they have diversified and how the duplicated are regulated. All these questions are addressed using oilseed rape (Brassica napus) and its related species as models.

Résultats marquants :

Publications représentatives :

M. Cifuentes, F. Eber, M.O. Lucas, M. Lode, AM Chèvre and E. Jenczewski. Repeated polyploidy drove different levels of crossover suppression between homeologous chromosomes in Brassica napus allohaploids The Plant Cell 22: 2265-2276

L. Grandont, M. Leflon, F. Eber, V. Huteau, O. Coriton, L. Chelysheva, Jenczewski E and AM Chèvre. Crossovers get a boost in Brassica triploid and tetraploid digenomic hybrids The Plant Cell 22: 2253-2264

M. Cifuentes, L. Grandont, G. Moore, AM Chèvre and Eric Jenczewski (2010) Genetic regulation of meiosis in polyploid species: new insights into an old question. The New Phytologist 186(1):29-36.

E. Szadkowski, F. Eber, V. Huteau, O. Coriton, M. Manzanares-Dauleux, R. Delourme, C. Huneau, B. Chalhoub, E. Jenczewski and AM. Chèvre (2010) The first meiosis in newly synthesized Brassica napus: a genome blender? The New Phytologist 186(1):102-112

S. Nicolas, M. Leflon, H. Monod, F. Eber, O. Coriton, V. Huteau, A.-M. Chèvre et E. Jenczewski (2009) Genetic regulation of meiotic crossovers between related genomes in Brassica napus haploids and hybrids. The Plant Cell 21: 373-385

Pouilly N., R. Delourme, K. Alix and E. Jenczewski (2008) Repetitive sequence-derived markers tag centromeres and telomeres and provide insights into chromosome evolution in Brassica napus. Chromosome Research 16: 686-700.

S. Nicolas, G. LeMignon, F. Eber, O. Coriton, H. Monod, V. Clouet, V. Huteau, A. Lostanlen, R. Delourme, B. Chalhoub, C. D. Ryder, A.-M. Chèvre et E. Jenczewski (2007) Homeologous recombination is responsible for most of the rearrangements that occur during meiosis of Brassica napus haploids. Genetics. 175: 487-503

Z. Liu, K. Adamczyk, M. Manzanares-Dauleux, F. Eber, M.-O. Lucas, R. Delourme, A.-M. Chèvre et E. Jenczewski (2006) Mapping PrBn and Other Quantitative Trait Loci Responsible for the Control of Homoeologous Chromosome Pairing in Oilseed Rape (Brassica napus L.) Haploids. Genetics. 174(3):1583-96

W. Albertin, P. Brabant, O. Catrive, F. Eber, E. Jenczewski, A.M. Chèvre et H. Thiellement (2005) Autopolyploidy in cabbage (Brassica oleracea L.) does not alter significantly the proteomes of green tissues. Proteomics 5: 2131-2139

E. Jenczewski et K. Alix. (2004) From diploids to allopolyploids: the emergence of pairing control genes. Critical Reviews in Plant Sciences 23(1): 21-45

E. Jenczewski, F. Eber, A. Grimaud, S. Huet, M.O. Lucas, H. Monod et A.M. Chèvre (2003) PrBn: a major gene controlling homoeologous pairing in oilseed rape (Brassica napus) dihaploids. Genetics 164: 645-654.

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